Genetic basis of atherosclerosis: part II: clinical implications.
نویسندگان
چکیده
Knowledge of genetic factors in the etiology of coronary heart disease has not so far been adequately utilized in attempts to combat premature CHD. The time has now come to utilize genetic information in a setting of family-oriented preventive medicine. This approach would greatly improve the efficiency of preventive efforts, utilizing predictive genetic testing and targeting counseling on those who need it most.1
منابع مشابه
Genetic basis of atherosclerosis: part I: new genes and pathways.
Atherosclerosis, the primary cause of coronary heart disease (CHD), involves numerous cell types and organs and a number of disparate physiological processes (see Figure 1).1–3 It is not surprising, then, that the genetic basis of CHD is complex. This complexity is clearly illustrated by studies of rodent models; for example, experiments with transgenic and gene-targeted mice have revealed 100 ...
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ورودعنوان ژورنال:
- Circulation
دوره 110 14 شماره
صفحات -
تاریخ انتشار 2004